eyes

Peer-reviewed publications

Velez G, Weingarden AR, Lei H, Kazlauskas A, Gao G. SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified Müller cell- induced rabbit models. Invest Ophthalmol Vis Sci. 2013 Feb 19;54(2):1392-7. doi10.1167/iovs.12-10320 PMID: 23341018

Velez G, Weingarden AR, Tucker BA, Lei H, Kazlauskas A, Young MJ. Retinal pigment epithelium and Muller progenitor cell interaction increase Müller progenitor cell expression of PDGFR and ability to induce proliferative vitreoretinopathy in a rabbit model. Stem Cells Int 2012;2012:106486. Epub 2012 Aug 23. PMID: 22966235

Lei H, Rheaume MA, Velez G, Mukai S, Kazlauskas A. Expression of PDGFR is a determinant of the PVR potential of ARPE19 cells. Invest Ophthalmol Vis Sci August 2011;52: 5016-5021. PMID: 21642621

Lei H, Velez G, Cui J, Matsubara J, Kazlauskas A. Pathologic signaling of PDGFR alpha involves chronic activation of Akt and suppression of p53. Mol Cell Biol 2011 May; 31(9):1788-99. Epub 2011 Feb28. PMID: 21357737

Lei H, Velez G, Cui J, Samad A, Maberley D, Matsubara J, Kazlauskas A. N-Acetylcysteine suppresses retinal detachment in an experimental model of PVR. Am J Pathol 2010 Jul:177(1):132-40. Epub 2010 May 20. PMID: 20489144

Lei H, Velez G, Hovland P, Hirose T, Gilbertson D, Kazlauskas A. Growth factors outside of the PDGF family drive experimental PVR. Invest Ophthalmol Vis Sci 2009 July; 50(7):3394-403. PMID: 19324843

Lei H, Velez G, Hovland P, Hirose T, Kazlauskas A. Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 2008 Jan; 49(1): 42-8. PMID: 18172073

Lei H, Hovland P, Velez G, Haran A, Gilbertson D, Hirose T, Kazlauskas A. A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 2007 May; 48(5):2335-42. PMID: 17460299

Buggage RR, Levy-Clarke G, Sen HN, Ursea R, Srivastava SK, Suhler EB, Altemare C, Velez G, Ragheb J, Chan CC, Nussenblatt RB, Bamji AT, Sran P, Waldmann T, Thompson DJ. A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behcet's disease. Ocul Immunol Inflamm. 2007 Mar-Apr;15(2):63-70. PMID: 17558830

retinal detachmentVelez G, Kansupada K, Csaky K, Reed GF, Whitcup SM, Nussenblatt RB. Serous Retinal Detachment in Posterior Uveitis. Ann Ophthalmol 2004; 36(2):103-110.

Nussenblatt RB, Thompson DJ, Li Z, Chan CC, Peterson JS, Robinson RR, Shames RS, Nagarajan S, Tang MT, Mailman M, Velez G, Roy C, Levy-Clarke GA, Suhler EB, Djalilian A, Sen HN, Al-Khatib S, Ursea R, Srivastava S, Bamji A, Mellow S, Sran P, Waldmann TA, Buggage RR. Humanized anti-interleukin-2 (IL-2) receptor alpha therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administration. J Autoimmun. 2003 Nov; 21(3):283-93. PMID: 14599854

Velez G, Weiter JJ. Cataract extraction and age-related macular degeneration: associations, diagnosis and management. Seminars in Ophthalmology 2002 Sep-Dec; 17(3-4):187-195. PMID: 12759849

Velez G, Boldt HC, Whitcup SM, Nussenblatt RB, Robinson MR. Local methotrexate and dexamethasone phosphate for recurrent primary intraocular lymphoma. Ophthal Surg and Lasers 2002; 33:329-333. PMID: 12134997

Velez G, Chan CC, Csaky KG. Fluorescein angiographic findings in primary intraocular lymphoma. Retina 2002; 22:37-43. PMID: 11884876

Velez G, Yuan P, Sung C, Tansey G, Reed GF, Chan CC, Nussenblatt RB, Robinson MR. Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma. Arch Ophthalmol 2001; 119:1518-1524. PMID: 11594954

Velez G, Buggage RR. Interleukin-10 and intraocular-central nervous system lymphoma. Ophthalmology 2001; 108(3):427-428. PMID: 11237884

Velez G, Roy CE, Whitcup SM, Chan CC, Robinson MR. High dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis. Am J Ophthalmol 2001; 131(3):396-397. PMID: 11239885

Velez G, de Smet MD, Whitcup SM, Robinson MR, Nussenblatt RB, Chan CC. Iris involvement in primary intraocular lymphoma: report of two cases and review of the literature. Surv Ophthalmol 2000; 44:518-526. PMID: 10906383

Velez G, Whitcup SM. New developments in sustained release drug delivery for the treatment of intraocular disease. Br J Ophthalmol 1999; 83:1225-1229. PMID: 10535845

Buggage RR, Velez G, Myers-Powell B, Shen D, Whitcup SM, Chan CC. Primary intraocular lymphoma with a low interleukin 10 to interleukin 6 ratio and heterogeneous IgH gene rearrangement. Arch Ophthalmol 1999; 117:1239-42. PMID: 10496399




Books & Chapters

Velez G, Whitcup SM. Ophthalmologic Manifestations. in Vasculitis. Ed Gene V. Ball, S. Louis Bridges (Oxford University Press Inc, New York, NY; 2001), p. 80-101.




Presentations & Abstracts

Velez G.  A study of geographic atrophy as the footprint of choroidal neovascularization in age-related macular degeneration.  2017. Association for Research in Vision and Ophthalmology abstract 2331

Velez G.  De novo and recurrent polypoidal lesions are amenable to anti-VEGF therapy.  2016. Association for Research in Vision and Ophthalmology abstract 4964

Velez G.  Chlorhexidine gluconate antisepsis for intravitreal injection.  2015. Association for Research in Vision and Ophthalmology abstract 4179

Velez G.  Intravitreal triamcinolone acetonide with anti-VEGF therapy for the management of polypoidal choroidal vasculopathy.  2014. Association for Research in Vision and Ophthalmology abstract 3905

Velez G. Ranibizumab for the treatment of diabetic macular edema in patients treated with Bevacizumab.  2013. Association for research in Vision and Ophthalmology abstract 2395
 
Velez G, Roy A.  Surface substrates affect the behavior and survival of Müller glia derived stem cells.  2012. Association for Research in Vision and Ophthalmology abstract 5917

tomographyVelez G, Lei H, Kazlauskas A, Kaushal S, Young M.  SU9518 inhibits proliferative vitreoretinopathy (PVR) in a Muller cell rabbit model of PVR. 2011.  Association for Research in Vision and Ophthalmology abstract 2065.

Lei H, Rheaume MA, Velez G, Mukai S, Kazlauskas A.  Expression of PDGFRa in retinal pigment epithelial cells promotes experimental proliferative vitreoretinopathy.  2011. Association for Research in Vision and Ophthalmology abstract 6590.

Velez G, Kazlauskas A, Young M.  SU 9518 inhibits proliferative vitreoretinopathy (PVR) in a rabbit model.  2010. Association for Research in Vision and Ophthalmology abstract 6086.

McRee SK, Tucker B, Bradbury MJ, Young M, Velez G.  Indocyanine green (ICG) induces increased Muller cell expression of adhesion molecules and membrane metalloproteinases in vitro.  2010. Association for Research in Vision and Ophthalmology abstract 5762.

Lei H., Velez G, Kazlauskas A.  Indirect activation of PDGFR alpha engages a PI3K/AKT/p53 dependent pathway that promotes cellular responses intrinsic to PVR.  2010. Association for Research in Vision and Ophthalmology abstract 6084.

Velez G, Tucker BA, Weingarden AR, Young, MJ.  Mueller cell de-differentiation leads to increased expression of platelet-derived growth factor receptor and retinal pigment epithelium cell markers.  2009.  Association for Research in Vision and Ophthalmology abstract 1295

Bradbury MJ, Velez G.  Combined intravitreal bevacizumab and photodynamic therapy for the treatment of very resistant choroidal neovascularization in age-related macular degeneration. 2009. Association for Research in Vision and Ophthalmology abstract 1915

Weingarden AR, Tucker BA, Lei H, Young MJ, Velez G.  Upregulation of platelet-derived growth factor receptor alpha in RPE and Muller cell co-cultures.  2009. Association for Research in Vision and Ophthalmology abstract 2707

Kazlauskas A, Lei H, Velez G.  Growth factors outside of the PDGF family drive experimental PVR.  2009. Association for Research in Vision and Ophthalmology abstract 6227

Lei H, Velez G, Kazlauskas A.  The role of growth factors outside of the PDGF family in experimental proliferative vitreoretinopathy.  2008. Association for Research in Vision and Ophthalmology abstract 4896

Velez G, Bradbury MJ.  Combined intravitreal bevacizumab (Avastin) and triamcinolone acetonide (Kenalog) for the treatment of choroidal neovascularization (CNV) associated with age-related macular degeneration (ARMD).  2008. Association for Research in Vision and Ophthalmology abstract 558

Velez G, Lei H, Kazlauskas A.  Comparison of fibroblasts and RPE cells for their ability to induce PVR in rabbits.  2007. Association for Research in Vision and Ophthalmology abstract 5778

Bradbury M, Velez G.  Intravitreal Avastin vs. laser photocoagulation for the treatment of peripapillary choroidal neovascularization.  2007. Association for Research in Vision and Ophthalmology abstract 1460

Velez G, Lei H, Kazlauskas A.  Intravitreal STI571 inhibition of proliferative vitreoretinopathy in an experimental rabbit model is dose dependent.  2006. Association for Research in Vision and Ophthalmology abstract 4685

Lei H, Hovland P, Velez G, Eriksson U, Gilbertson DG, Hirose T, Kazlauskas A.  A potential role for PDGF-CC in proliferative vitreoretinopathy.  2006. Association for Research in Vision and Ophthalmology Abstract 3828

Velez G, Kazlauskas A.  Intravitreal STI571 inhibits development of proliferative vitreoretinopathy in an experimental rabbit model.  2005. Association for Research in Vision and Ophthalmology abstract 5519

Velez G, Weiter JJ.  Assessment and comparison of risk factors in subretinal hemorrhages associated with choroidal neovascularization and suprachoroidal hemorrhages.  2003. Association for Research in Vision and Ophthalmology abstract 4921

Velez G, Silk W, Csaky KG.  Correlation of in-vivo fluorescein angiography findings with in-vitro fluorescein uptake by monocytes. 2002. Association for Research in Vision and Ophthalmology abstract 516

Velez G, Baudo TA, Luu RP, Murphy RP, Glaser BM.  High Speed ICG Angiographic characterization of feeder vessels to choroidal neovascularization associated with ocular inflammatory disease.  Invest Ophthalmol Vis Science 2001; 42(4): S230.  Abstract 1240

Glaser BM, Baudo TA, Velez G, Luu JK, Murphy RP.  Feeder vessel treatment for age-related macular degeneration with classic choroidal neovascularization (CNV).  Invest Ophthalmol Vis Science 2001; 42(4): S231.  Abstract 1243

Luu JK, Baudo TA, Velez G, Murphy RP, Glaser BM.  Internal tamponade without tPA for the treatment of submacular hemorrhage in age-related macular degeneration.  Invest Ophthalmol Vis Science 2001; 42(4): S234.  Abstract 1264

retinaBaudo TA, Velez G, Luu JK, Murphy RP, Glaser BM.  Incidence of predominantly classic choroidal neovascular membranes (CNV) in exudative age related macular degeneration (AMD): percentage of new patients eligible for photodynamic therapy with Vereteporfin.  Invest Ophthalmol Vis Science 2001; 42(4): S438.  Abstract 2360

Velez G, Kansupada K, Csaky KG, Whitcup SM, Nussenblatt RB.  Serous retinal detachment in patients with uveitis.  AAO, 2000

Velez G, King BA, Yuan P, Whitcup SM, Robinson MR. Thalidomide analogue (EM138) sustained- release implants to treat choroidal neovascularization associated with macular degeneration.  Invest Ophthalmol Vis Science 2000;41(4): S180.

Buggage RR, Velez G, Chan CC, Smith JA.  New keratoconjunctival findings in HTLV-1 infection.  American Uveitis Society Meeting, AAO, 1999.

Velez G, Robinson MR, Durbin T,  et al.  Thalidomide sustained release devices for choroidal neovascularization: an in-vitro analysis.  Invest Ophthalmol Vis Science 1999; 40(4): S448

Brusie SR, Velez G, Wagner DG, Cupples HP.  Epidemiology and long-term outcomes of open-globe missile injuries among children.  Invest Ophthalmol Vis Science 1999; 40(4): S168

Velez G, Wagner DG.  The role of scleral buckle in the management of open globe injuries.  Invest Ophthalmol Vis Science 1998; 39(4): Abstract 4648

Bonsall D, Territo J, Velez G, Chrousos G.  Vertical Strabismus after cataract surgery.  AAPOS, 1998

Velez G, Wagner DG.  Epidemiology of open globe injuries and the elderly.  Invest Ophthalmol Vis Science 1997;38(4): S282